• Epidemiol. Infect. · Jul 2020

    Epidemiological and clinical characteristics of a familial cluster of COVID-19.

    • Yong Sun, Lin Tian, Xiaomei Du, Hua Wang, Yueshan Li, and Rangbing Wu.
    • Department of Endocrinology and Metabolism, Dazhou Central Hopsital, Dazhou, Sichuan, China.
    • Epidemiol. Infect. 2020 Jul 7; 148: e145.

    AbstractWe report a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involving five patients in a family cluster in Dazhou, China, including the epidemiological, clinical, laboratory and radiological findings. Three-generation transmission was observed. Through epidemiological investigation, we observed asymptomatic transmission to a cohabiting family member, as well as person-to-person transmission of SARS-CoV-2 outside Wuhan city. The asymptomatic transmission demonstrated here provides evidence that there could be a greater risk of Coronavirus Disease 2019 (COVID-19) spread. This cluster also demonstrated that COVID-19 is transmissible during the incubation period of an asymptomatic person. Early isolation and treatment, stressing prevention of cluster outbreaks, could help prevent further spread of the epidemic.

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