• Mustafa Erbayrak, Cansel Turkay, Elife Eraslan, Hulya Cetinkaya, Benan Kasapoglu, and Mehmet Bektas.
• Gastroenterology Department, Fatih University Hospital, Ankara, Turkey.
• Clinics (Sao Paulo). 2009 May 1; 64 (5): 421-5.

IntroductionInvasive and non-invasive tests can be used to evaluate the activity of inflammatory bowel diseases.ObjectiveThe aim of the present study was to investigate the role of fecal calprotectin in evaluating inflammatory bowel disease activity and the correlation of fecal calprotectin with the erythrocyte sedimentation rate and C reactive protein values in inflammatory bowel disease.MethodSixty-five patients affected with inflammatory bowel disease were enrolled. Twenty outpatients diagnosed with inflammatory bowel disease comprised the control group.ResultsIn the present study, all patients in the control group had an fecal calprotectin value lower than the cut-off point (50 mg/kg).ConclusionIn conclusion, fecal calprotectin was found to be strongly associated with colorectal inflammation indicating organic disease. Fecal calprotectin is a simple and non-invasive method for assessing excretion of macrophages into the gut lumen. Fecal calprotectin values can be used to evaluate the response to treatment, to screen asymptomatic patients, and to predict inflammatory bowel disease relapses.

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