• Clinical science · Apr 2020

    Editorial

    ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19.

    • Rhian M Touyz, Hongliang Li, and Christian Delles.
    • Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, U.K.
    • Clin. Sci. 2020 Apr 17; 134 (7): 747-750.

    AbstractAngiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.© 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

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