• Manon G van der Meer, Yolande Appelman, Karlijn H G Rutten, Yolanda van der Graaf, Hendrik M Nathoe, Pieter A Doevendans, Michelle Smit, Emmy Verheij, Anne Botermans, and Frans H Rutten.
• Cardiology, University Medical Center Utrecht, Utrecht, Utrecht, The Netherlands.
• BMJ Open. 2019 Nov 19; 9 (11): e031613.

ObjectivesPrevious hospital-based studies have suggested delayed recognition of acute coronary syndrome (ACS) in women. We wanted to assess differences in symptom presentation or triage among women and men who contacted primary care out-of-hours services (OHS) for chest discomfort.DesignRetrospective observational study.SettingPrimary care OHS.Participants276 women and 242 men with chest discomfort who contacted a primary care OHS in the Netherlands in 2013 and 2014.Main Outcome MeasuresDifferences between women and men regarding symptom presentation and urgency allocation.Results8.4% women and 14.0% men had ACS. Differences in symptoms between patients with and without ACS were in general small, for both women and men. In women with ACS compared with women without ACS, mean duration of telephone calls was discriminative; 5.22 (SD 2.53) vs 7.26 (SD 3.11) min, p value=0.003. In men, radiation of pain (89.3% vs 54.9%, p value=0.011) was discriminative for ACS, and stabbing chest pain (3.7% vs 24.0%, p value=0.014) for absence of ACS . Women and men with chest discomfort received similar high urgency allocation (crude and adjusted OR after correction for ACS and age; 1.03 (95% CI 0.72 to 1.48) and 1.04 (95% CI 0.72 to 1.52), respectively). Women with ACS received a high urgency allocation in 22/23 (95.7%) and men with ACS in 30/34 (88.2%), p value=0.331.ConclusionsDiscriminating ACS in patients with chest discomfort who contacted primary care OHS is difficult in both women and men. Women and men with chest discomfort received similar high urgency allocation.© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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