• Jia-Chi Wang, Kon-Ping Lin, Kwong-Kum Liao, Yue-Cune Chang, Kevin A Wang, Yu-Fang Huang, and Jan-Wei Chiu.
• Department of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Beitou District, Taipei City, 11217, Taiwan.
• Muscle Nerve. 2018 Sep 1; 58 (3): 402-406.

IntroductionThe sonographic changes of the median nerve after steroid injection for carpal tunnel syndrome (CTS) still require investigation.MethodsSixty-two patients with CTS were included. The Boston Carpal Tunnel Questionnaire was administered, and ultrasonographic examinations were performed before and at 2, 6, and 12 weeks after steroid injection. At 12 weeks, general improvement was scored on a 6-point Likert scale.ResultsAfter treatment, the cross-sectional area (CSA) of the median nerve was significantly reduced at 2-, 6-, and 12-week follow-ups (for each, P < 0.001, analysis of variance). The "significant improvement" group (n = 39) had a significantly greater reduction in the CSA at the carpal tunnel inlet (P = 0.014) and CSA in the proximal carpal tunnel (P = 0.003) compared with the "little/no improvement" group (n = 23).DiscussionSonographic measurement of CSA may be considered complementary to the standard clinical evaluation in monitoring of treatment response in patients with CTS. Muscle Nerve 58: 402-406, 2018.© 2018 Wiley Periodicals, Inc.

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