• Lisa Saidel-Odes, Abraham Borer, Francisc Schlaeffer, Ronit Nativ, Ilana Livshiz-Riven, Yonat Shemer, Rozalia Smolyakov, and Klaris Riesenberg.
• Infectious Diseases Institute, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, PO Box 151 Beer-Sheva, Israel 84101. saidelod@bgu.ac.il
• Int. J. Infect. Dis. 2011 Jul 1; 15 (7): e470-4.

ObjectivesTo determine the risk factors for community-acquired pneumonia (CAP) with influenza A/H1N1 flu in our region.MethodsAdult patients with CAP from July 2009 to February 2010 who were screened for influenza A/H1N1 were identified retrospectively. This was a retrospective case-control study. Cases had CAP with influenza A/H1N1 and controls had CAP without influenza A/H1N1. Patient files were reviewed for demographics, clinical characteristics, treatment, and outcome.ResultsThree hundred and eight patients with CAP were identified: 107 cases and 201 controls. For cases vs. controls there were significant differences in the following: median age (40 (range 18-82) vs. 56 (range 18-89) years; p<0.001), female gender (63.6% vs. 44.3%; p<0.05), Bedouin Arab origin (41.1% vs. 26.4%; p<0.05), pyrexia (97.6% vs. 88.5%; p<0.01), cough (96.3% vs. 75%; p<0.05), admission to the intensive care unit (18.7% vs. 10.6%; p<0.05), and CURB-65 score ≥ 3 (2.8% vs. 11.4%; p<0.05). Laboratory values including white blood cell (WBC) and platelet counts were lower in cases than in controls, whereas creatine phosphokinase and lactate dehydrogenase levels were higher (p<0.01). By logistic regression models, young age, Bedouin origin, and lower WBC and platelet counts were independent risk factors for the acquisition of CAP with influenza A/H1N1.ConclusionsIn our region CAP with influenza A/H1N1 occurred in younger females of Bedouin Arab origin with less co-morbidity. No difference in mortality was found. We believe that inequalities in socioeconomic conditions could explain our findings.Copyright © 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

32 keywords...

hide…