• A E Owais, R F Bumby, and J MacFie.
• Scarborough General Hospital, UK. anwarowais@nhs.net
• Aliment. Pharmacol. Ther. 2010 Sep 1; 32 (5): 628-36.

BackgroundThe importance of adequate nutritional support in selected patient groups is well established. Traditionally, the amounts of macronutrients provided have been based on a perceived need to achieve, if not exceed, energy and protein balance. In recent years, there has been increasing interest in the concept of 'permissive underfeeding'.AimTo determine whether or not there is evidence of benefit for permissive underfeeding in selected groups.MethodsStudies were identified from MEDLINE, Embase and PubMed databases and the Cochrane collaboration. The search was limited from January 1950 to January 2010. Further searches were made from the references of original articles. The literature search revealed 591 abstracts of relevant studies. All abstracts were initially reviewed by the primary author (AO) and those that did not fulfil the inclusion criteria were discarded. The remaining articles were requested and were reviewed independently by two authors (AO, JM).ResultsTwelve studies were included in the final analysis. Eight of these were randomized interventional trials. Three were prospective cohort studies and one was a retrospective analysis.ConclusionThis review suggests that permissive underfeeding may be associated with improved outcomes and reduced morbidity in patients requiring short-term nutritional support.2010 Blackwell Publishing Ltd.

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