• Med. Sci. Monit. · Dec 2011

    Case Reports

    Gabapentin in the treatment of dementia-associated nocturnal agitation.

    • Jitka Buskova, Petr Busek, and Sona Nevsimalova.
    • Department of Neurology - Sleep Disorders Center, 1st Faculty of Medicine and General Teaching Hospital, Charles University, Prague, Czech Republic.
    • Med. Sci. Monit. 2011 Dec 1; 17 (12): CS149-51.

    BackgroundNocturnal sleep of patients suffering from various forms of dementia is often impaired by nocturnal agitation or nocturnal wandering. Anticonvulsives such as carbamazepine or valproate are reported to have some therapeutic efficacy, but there is little information about other drugs suitable for treatment of this condition.Case ReportOur patient, a 77-year-old Czech woman with incipient vascular dementia, received gabapentin 400mg at bedtime for 6 months and showed convincing improvement.ConclusionsGabapentin was very effective in treating nocturnal agitation.

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