• Lia Restimulia, Dwi Reno Pawarti, and Haris Mayaguyang Ekorini.
• Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Airlangga University, Jl. Prof. Dr Moestopo No. 47, Surabaya 60132, Indonesia.
• Open Access Maced J Med Sci. 2018 Aug 20; 6 (8): 1405-1409.

BackgroundAllergic diseases and vitamin D deficiency were found to have a relationship. However, there was limited number of studies on the relationship between vitamin D with allergic rhinitis (AR) and total nasal symptom scores (TNSS), particularly in determining the cut-off points of serum vitamin D levels which correlated to AR.AimAs this particular study has never been conducted in Indonesia, the main objective of this study was to investigate this issue.MethodsThe research was conducted at Dr Soetomo Hospital, Surabaya in January 2017. A group of 30 subjects were recruited using consecutive sampling. Levels of serum vitamin D were measured using electrochemiluminescence immunoassay (ECLIA) method while the total nasal symptom scores were obtained by accumulating all the nasal symptoms. Data of serum vitamin D levels and TNSS were analysed statistically with the Pearson correlation test.ResultsIt was found that the mean of serum 25(OH) vitamin D levels (9.13 ng/mL) of the AR group was significantly lower than the non-AR group (26.22 ng/mL) (P = 0.000). The vitamin D cut-off points which correlated to AR was about 12.83 ng/mL (sensitivity = 80%; specificity = 100%). A Pearson correlation test found a strong, negative correlation between vitamin D levels and TNSS (P = 0.000; r = -0.800).ConclusionThere was a strong, negative correlation between serum vitamin D levels with AR and TNSS. The cut-off points of serum vitamin D levels correlated to AR were approximately12.83 ng/mL. Thus, further research needs to be conducted.

4 keywords...

hide…