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- Akbarshakh Akhmerov and Eduardo Marbán.
- From the Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
- Circ. Res. 2020 May 8; 126 (10): 1443-1455.
AbstractInfection with the severe acute respiratory syndrome novel coronavirus produces a clinical syndrome known as 2019 novel coronavirus disease (COVID-19). When severe, COVID-19 is a systemic illness characterized by hyperinflammation, cytokine storm, and elevations of cardiac injury biomarkers. Here, we review what is known about the pathophysiology of COVID-19, its cardiovascular manifestations, and emerging therapeutic prospects. In this rapidly moving field, this review was comprehensive as of April 3, 2020.
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