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Clinical Trial
The pattern of Tpeak-Tend and QT interval, and J wave during therapeutic hypothermia.
- Sun-Mi Kim, Hwang Gyo-Seung GS Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea. Electronic address: hwanggs@medimail.co.kr., Jin-Sun Park, Jeoung-Sook Shin, Gi-Woon Kim, Hyoung-Mo Yang, So-Yeon Choi, Yoon Myeong-Ho MH Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea., Joon-Han Shin, and Seung-Jea Tahk.
- Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
- J Electrocardiol. 2014 Jan 1; 47 (1): 84-92.
Background And PurposeThe electrocardiogram manifestations of hypothermia include J waves and prolongation of QT intervals. This study described changes in repolarization patterns during therapeutic hypothermia (TH).MethodsWe measured the QTc and the interval from the peak to the end of the T wave (TpTe) from the V4 and V6 leads in 20 patients with TH. The TpTe was also expressed as a ratio to the duration of QT ([TpTe/QT]×100%), and to the corrected value for heart rate (TpTe/√RR).ResultsThe QTc became prolonged in all patients during TH. While the TpTe/√RR did not change, the ([TpTe/QTe]×100%] decreased significantly during TH. The J wave developed during TH in seven patients. With one patient, ventricular fibrillation occurred preceded by an abnormal J wave and prolonged TpTe during TH.ConclusionsQTc prolongation without TpTe increase or abnormal J wave may not be arrhythmogenic during TH.Copyright © 2014 Elsevier Inc. All rights reserved.
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