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J Microbiol Immunol Infect · Jun 2020
TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib.
- Dandan Wu and Xuexian O Yang.
- Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA; College of Agronomy, Hunan Agricultural University, Changsha, Hunan, 410128, China.
- J Microbiol Immunol Infect. 2020 Jun 1; 53 (3): 368-370.
AbstractCOVID-19 emerges as a pandemic disease with high mortality. Development of effective prevention and treatment is an urgent need. We reviewed TH17 responses in patients with SARS-CoV-2 and proposed an FDA approved JAK2 inhibitor Fedratinib for reducing mortality of patients with TH17 type immune profiles.Copyright © 2020. Published by Elsevier B.V.
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