• La Tunisie médicale · May 2011

    Review

    [Faecal calprotectin in inflammatory bowel diseases: review].

    • Lamia Kallel, Monia Fekih, Jalel Boubaker, and Azza Filali.
    • Hopital la Rabta, Tunis, Tunisie.
    • Tunis Med. 2011 May 1; 89 (5): 425-9.

    BackgroundThe clinical course of inflammatory bowel disease (IBD) is characterised by a succession of relapses and remissions. A regular and a long term monitoring of such patients is required. Faecal markers, especially calprotectin's use, seem to be useful in these patients. Faecal calprotectin is a reliable maker of intestinal inflammation in IBD. Its level is assessed by a simple and a non invasive test.AimWe proposed to review main indications and study results of faecal calprotectin test use in IBD patients.MethodsReview of literature.ResultsFaecal calprotectin assessment isn't an IBD specific test. Selective use is required to have a good benefit-cost ratio. Prediction of relapses in asymptomatic patients as well as post operative reccurence seems to be the main indications for its use.ConclusionMucosal healing assessment after anti-TNF treatment can also be an interesting indication although it isn't well evaluated.

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