• Silvia Vírseda, María Alejandra Restrepo, Elena Arranz, Purificación Magán-Tapia, Mario Fernández-Ruiz, de la Cámara Agustín Gómez AG, José María Aguado, and Francisco López-Medrano.
• Unit of Infectious Diseases, University Hospital 12 de Octubre, Avda. de Córdoba s/n., 28041 Madrid, Spain.
• Vaccine. 2010 Jul 5; 28 (30): 4751-7.

AbstractInfluenza vaccination coverage among health-care workers (HCWs) remains the lowest compared with other priority groups for immunization. Little is known about the acceptability and compliance with the pandemic (H1N1) 2009 influenza vaccine among HCWs during the current campaign. Between 23 December 2009 and 13 January 2010, once the workplace vaccination program was over, we conducted a cross-sectional, questionnaire-based survey at the University Hospital 12 de Octubre (Madrid, Spain). Five hundred twenty-seven HCWs were asked about their influenza immunization history during the 2009-2010 season, as well as the reasons for accepting or declining either the seasonal or pandemic vaccines. Multiple logistic-regression analysis was preformed to identify variables associated with immunization acceptance. A total of 262 HCWs (49.7%) reported having received the seasonal vaccine, while only 87 (16.5%) affirmed having received the pandemic influenza (H1N1) 2009 vaccine. "Self-protection" and "protection of the patient" were the most frequently adduced reasons for acceptance of the pandemic vaccination, whereas the existence of "doubts about vaccine efficacy" and "fear of adverse reactions" were the main arguments for refusal. Simultaneous receipt of the seasonal vaccine (odds ratio [OR]: 0.27; 95% confidence interval [95% CI]: 0.14-0.52) and being a staff (OR: 0.08; 95% CI: 0.04-0.19) or a resident physician (OR: 0.16; 95% CI: 0.05-0.50) emerged as independent predictors for pandemic vaccine acceptance, whereas self-reported membership of a priority group was associated with refusal (OR: 5.98; 95% CI: 1.35-26.5). The pandemic (H1N1) 2009 influenza vaccination coverage among the HCWs in our institution was very low (16.5%), suggesting the role of specific attitudinal barriers and misconceptions about immunization in a global pandemic scenario.Copyright 2010 Elsevier Ltd. All rights reserved.

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