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- H Bachorzewska-Gajewska, J Malyszko, E Sitniewska, J S Malyszko, B Poniatowski, K Pawlak, and S Dobrzycki.
- Int. J. Cardiol. 2008 Jul 4; 127 (2): 290-1.
AbstractThe aim of the study was to assess whether NGAL and cystatin C could predict contrast-induced nephropathy in non-diabetic patients (n=60, mean age 60+/-11 years) with normal serum creatinine undergoing elective PCI. We found a significant rise in serum NGAL after 2, 4 and 8 h, and in urinary NGAL after 4, 8 and 24 h after PCI. Cystatin C rose significantly 8 and 24 h after the procedure. Prevalence of CIN was 10%. We found 90% sensitivity and 74% specificity of serum and 76% sensitivity and 80% specificity of urinary NGAL increase. NGAL may represent a sensitive early biomarkers of renal impairment after PCI.
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