• Mariam Naqvi, Shannon Thyne, Shweta Choudhry, Hui-ju Tsai, Daniel Navarro, Richard A Castro, Sylvette Nazario, Jose R Rodriguez-Santana, Jesus Casal, Alfonso Torres, Rocio Chapela, H Geoffrey Watson, Kelley Meade, Michael LeNoir, Pedro C Avila, William Rodriguez-Cintron, and Esteban González Burchard.
• University of California, San Francisco, California 94110, USA.
• J Asthma. 2007 Oct 1; 44 (8): 639-48.

AbstractSocioeconomic and environmental differences do not fully explain differences in asthma prevalence, morbidity, and mortality among Puerto Ricans, African Americans, and Mexican Americans. Differences in response to albuterol may be a factor. We compared bronchodilator responsiveness between these three populations. All groups demonstrated below expected responsiveness. Puerto Ricans of all ages and African American children with moderate-to-severe asthma demonstrated the lowest responsiveness overall. Among subjects with moderate-to-severe asthma, children were even less likely than adults to show the expected bronchodilator response. We conclude that ethnic-specific differences in bronchodilator drug responsiveness exist between Mexicans, Puerto Ricans, and African Americans with asthma. This may be of importance in asthma management.

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