• Xiu-fang Zhang, Xue-ming Liu, Xiao-feng Bao, Xian-jing Peng, Wen Zhang, and Jun Xu.
• Department of Ultrasonography, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
• Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 Jul 1; 35 (4): 444-7.

ObjectiveTo investigate the clinical value of real-time tissue elastography (RTE) in the diagnosis of breast cancer.MethodsOne hundred and twenty patients with breast lumps (135 lesions) were examined with B-mode imaging, color Doppler flowing imaging (CDFI) and RTE. The elastogram was graded using 5-score evaluating method. The postoperative pathological diagnosis was used as gold standard, and the sensitivity, specificity and accuracy of RTE and two-dimensional ultrasonography combined with RTE in diagnosis of breast cancer were calculated.ResultWhen the score >4 was set for cut-off criteria of malignancy, the sensitivity, specificity and accuracy of RTE was 85.45%, 83.75% and 84.4%, respectively. While two-dimensional ultrasonography combined with RTE was used, the sensitivity, specificity and accuracy increased up to 100%, 95% and 97%, respectively.ConclusionRTE combined with two-dimensional ultrasonography can improve the validity in the diagnosis of malignant breast lesions.

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