• Korean J Radiol · May 2020

    Case Reports

    Small Solitary Ground-Glass Nodule on CT as an Initial Manifestation of Coronavirus Disease 2019 (COVID-19) Pneumonia.

    • Tianyi Xia, Jiawei Li, Jiao Gao, and Xunhua Xu.
    • Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
    • Korean J Radiol. 2020 May 1; 21 (5): 545-549.

    AbstractThe 2019 novel coronavirus (2019-nCoV) outbreak in Wuhan, Hubei Province, China in 2019 led to large numbers of people being infected and developing atypical pneumonia (coronavirus disease 2019, COVID-19). Typical imaging manifestations of patients infected with 2019-nCoV has been reported, but we encountered an atypical radiological manifestation on baseline computed tomography (CT) images in three patients from Wuhan, China infected with the 2019-nCoV. Surprisingly, the only similar CT finding was a solitary sub-centimeter ground-glass nodule adjacent to bronchovascular bundles, which could be easily overlooked. In addition, the follow-up images in these patients showed how COVID-19 pneumonia evolved from these small nodules. The radiologic manifestation of the three cases will expand contemporary understanding of COVID-19.Copyright © 2020 The Korean Society of Radiology.

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