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- A Saiz, F Graus, F Valldeoriola, J Valls-Solé, and E Tolosa.
- Service of Neurology, Department of Medicine, Hospital Clínic i Provincial, University of Barcelona, Spain.
- Ann. Neurol. 1998 Mar 1; 43 (3): 400-3.
AbstractWe report on 2 patients who presented stiffness and spasms similar to those of stiff-man syndrome (SMS) that were limited to one leg for up to 11 years. Patients had serum glutamic acid decarboxylase (GAD) autoantibodies in high titer, clinical evidence of organ-specific autoimmunity, and electromyographic pattern of continuous motor unit activity with abnormally enhanced exteroceptive reflexes. The clinical and immunological profile suggests that this disorder may be a focal form of SMS.
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