• Diagnostics (Basel) · May 2020

    Review

    Saliva-Friend and Foe in the COVID-19 Outbreak.

    • Pingping Han and Sašo Ivanovski.
    • School of Dentistry, The University of Queensland, Herston, 4006 Queensland, Australia.
    • Diagnostics (Basel). 2020 May 9; 10 (5).

    AbstractThe coronavirus disease 2019 (COVID-19) outbreak, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global ongoing pandemic. Timely, accurate and non-invasive SARS-CoV-2 detection in both symptomatic and asymptomatic patients, as well as determination of their immune status, will facilitate effective large-scale pandemic control measures to prevent the spread of COVID-19. Saliva is a biofluid whose anatomical source and location is of particularly strategic relevance to COVID-19 transmission and monitoring. This review focuses on the role of saliva as both a foe (a common mode of viral transmission via salivary droplets and potentially aerosols) and a friend (as a non-invasive diagnostic tool for viral detection and immune status surveillance) in combating COVID-19.

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