• Neurology · Jan 2003

    Comparative Study

    A comparison of risk factors for recurrent TIA and stroke in patients diagnosed with TIA.

    • S Claiborne Johnston, Steve Sidney, Allan L Bernstein, and Daryl R Gress.
    • Neurovascular Service, Department of Neurology, University of California, San Francisco, USA. clay.johnston@ucsfmedctr.org
    • Neurology. 2003 Jan 28; 60 (2): 280-5.

    BackgroundSome spells consistent with TIA may be benign, such as those produced by migraine or migraine accompaniments in the elderly. Distinguishing these from embolic or thrombotic events may be difficult.MethodsEmergency department physicians identified patients who presented with a presumed TIA at one of 16 hospitals in Northern California from March 1997 through February 1998. Recurrent TIAs and strokes were recorded for 90 days afterwards.ResultsOf 1,707 patients in whom TIA had been diagnosed in the emergency department, 191 (11.2%) had a recurrent TIA and 180 (10.5%) had a stroke during 90-day followup. Independent risk factors for recurrent TIA were age >60 years (odds ratio 1.9; 95% CI 1.2 to 2.9; p = 0.003), history of multiple TIAs (odds ratio 2.9; 2.1 to 4.0; p < 0.001), duration of spell 10 minutes, diabetes, weakness, and speech impairment. Among the 30 patients with isolated sensory symptoms lasting ConclusionsIn patients in whom TIA has been diagnosed in the emergency department, risk factors for subsequent stroke and recurrent TIA are different. A subset of patients with presumed TIA has a benign short-term course with multiple brief TIAs more frequently characterized by sensory symptoms.

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