• Arq Neuropsiquiatr · Aug 2011

    Cognitive impairments in patients with low grade gliomas and high grade gliomas.

    • Eliane C Miotto, Aluizio Silva Junior, Clemar Corrêa Silva, Hector Navarro Cabrera, Melissa A R Machado, Glaucia R G Benute, Mara C S Lucia, Milberto Scaff, and Manoel Jacobsen Teixeira.
    • Department of Neurology, Hospital das Clinicas, University of São Paulo, Medical School, São Paulo SP, Brazil. ecmiotto@usp.br
    • Arq Neuropsiquiatr. 2011 Aug 1; 69 (4): 596-601.

    ObjectiveThe relationship between brain tumors and cognitive deficits is well established in the literature. However, studies investigating the cognitive status in low and high-grade gliomas patients are scarce, particularly in patients with average or lower educational level. This study aimed at investigating the cognitive functioning in a sample of patients with low and high-grade gliomas before surgical intervention.MethodThe low-grade (G1, n=19) and high-grade glioma (G2, n=8) patients underwent a detailed neuropsychological assessment of memory, executive functions, visuo-perceptive and visuo-spatial abilities, intellectual level and language.ResultsThere was a significant impairment on verbal and visual episodic memory, executive functions including mental flexibility, nominal and categorical verbal fluency and speed of information processing in G2. G1 showed only specific deficits on verbal and visual memory recall, mental flexibility and processing speed.ConclusionThese findings demonstrated different levels of impairments in the executive and memory domains in patients with low and high grade gliomas.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…