• Joint Bone Spine · Jan 2002

    Case Reports

    Dermatomyositis sine myositis and antisynthetase syndrome.

    • Ana Climent-Albaladejo, Encarnacion Saiz-Cuenca, Juan Rosique-Roman, Julian Caballero-Rodriguez, and Jose Galvez-Munoz.
    • Rheumatology unit, Hospital General Universitario Morales Meseguer, Murcia, Spain. Zuniga@um.es
    • Joint Bone Spine. 2002 Jan 1; 69 (1): 72-5.

    AbstractWe describe a 66-year-old woman with cutaneous lesions typical of classic dermatomyositis, clinical evidence of antisynthetase syndrome (arthritis, Raynaud's phenomenon, mechanic's hands and interstitial lung disease with anti-Jo-1 autoantibody) and lack of muscle disease after a full muscle evaluation that included clinical, enzymatic, electromyographic, magnetic resonance imaging and histological studies. The patient did not develop myositis after 9 years of clinical disease. The association of dermatomyositis sine myositis with antisynthetase antibodies suggests that the characteristic skin lesions are closely linked with dermatomyositis on the basis of the similar clinical and serological features of both dermatomyositis sine myositis and classic dermatomyositis.

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