-
Ann. N. Y. Acad. Sci. · Oct 2006
Review Meta Analysis Comparative StudyAssociation of SUMO4, as a candidate gene for IDDM5, with susceptibility to type 1 diabetes in Asian populations.
- Shinsuke Noso, Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata, Katsuaki Asano, Yoshihisa Hiromine, Shigetaka Sugihara, Inkyu Lee, Eiji Kawasaki, Takuya Awata, and Toshio Ogihara.
- Department of Endocrinology, Diabetes and Metabolism, Kinki University School of Medicine, 377-2 Ohno-higashi, Sayama-shi, Osaka 589-8511, Japan.
- Ann. N. Y. Acad. Sci. 2006 Oct 1; 1079: 41-6.
AbstractRecent study demonstrated that M55V variant in SUMO4 at IDDM5 was associated with susceptibility to type 1 diabetes. Subsequent studies, however, showed inconsistency in the association. To clarify the population-wide effect on the association of SUMO4 with type 1 diabetes, we have performed meta-analysis including our own data in Asian populations, which confirmed a highly significant association in Asian populations (summary odds ratio [OR]: 1.29, P = 7.0 x 10(-6)), but indicated significant heterogeneity in the genetic effect of the SUMO4 gene on type 1 diabetes among diverse ethnic groups. These observations indicated the association of SUMO4 with type 1 diabetes in Asian populations.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..