• Rev Esp Anestesiol Reanim · Jun 2016

    Characteristics of particulate and non-particulate corticosteroids. Indications for their use in chronic pain treatments.

    • J M Orduña-Valls, C L Nebreda-Clavo, P López-Pais, D Torres-Rodríguez, M Quintans-Rodríguez, and J Álvarez-Escudero.
    • Servicio de Anestesiología Reanimación y Tratamiento del Dolor, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España. Electronic address: dr.orduna.dolor@gmail.com.
    • Rev Esp Anestesiol Reanim. 2016 Jun 1; 63 (6): 333-46.

    AbstractCorticosteroids been used frequently in pain treatments since the middle of last century (1952). Due to a review of the complications as a result of their application in epidural injections, the United States of America Food and Drug Administration (FDA) issued an «alert controversy» requesting that a warning label should be added to injectable corticosteroids, where risks must be described (loss of sight, brain damage, paralysis and death) when administering by this route. It must be mentioned that there are different types of corticosteroids with diverse characteristics, which as a result, may produce different side-effects. Due to the aforementioned developments, the controversies that have arisen, and the lack of well-conducted studies on the use of steroids in epidural injections, we must begin by reviewing their indications in different pain conditions. Copyright © 2016 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

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