• J A Santos Rodriguez and J Mancebo Cortés.
• Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: jsantosr@santpau.cat.
• Med Intensiva. 2020 Nov 1; 44 (8): 485-492.

ObjectiveTo explain mortality in the ICU and in hospital among patients subjected to invasive mechanical ventilation.DesignA prospective, 9-month observational cohort study was carried out.SettingA Department of Intensive Care Medicine.PatientsConsecutive patients requiring invasive mechanical ventilation were followed-up on until hospital discharge or death.InterventionsNone.Interest VariablesDate of admission, day of first spontaneous breathing test, length of mechanical ventilation, final extubation date, days in ICU, days in hospital or discharge from ICU, SAPS-3 score, WIND study classification, day of death, hospital discharge.ResultsThere were 266 patients: 40 in group 0 of the WIND classification (15%; 95% CI 11-20%); 166 in group 1 (62%; 95% CI 56-68%); 38 in group 2 (14%; 95% CI 11-19%); and 22 in group 3 (8%; 95% CI 6-12%. Logistic regression analysis showed group 3 to have the highest hospital mortality (group 3 vs. group 1; odds ratio 4.0; 95% CI 1.5-10.8; P=.007). However, Cox regression analysis showed no significant differences (hazard ratio group 3 vs. group 1, 1.6; 95% CI 0.7-3.4; P=ns).ConclusionIn our study, considering exposure time, the probability of mortality was the same among the 3 different groups of patients with at least one spontaneous breathing test.Copyright © 2019 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

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