• Revue médicale suisse · Apr 2020

    [Hematology in the time of COVID-19].

    • Mathilde Gavillet, Nathalie Rufer, Francesco Grandoni, Jeanette Carr Klappert, Maxime G Zermatten, Anne Cairoli, Giorgia Canellini, Lorenzo Alberio, Michel A Duchosal, Olivier Spertini, and Sabine Blum.
    • Service et Laboratoire central d'Hématologie, Département d'Oncologie et Département des Laboratoires et de Pathologie, CHUV, 1011 Lausanne.
    • Rev Med Suisse. 2020 Apr 29; 16 (N° 691-2): 823-826.

    AbstractThe COVID-19 pandemic impacts the hematology practice. Intensive chemotherapies for high-grade lymphomas and acute leukemias, multiple myeloma treatments and most hematopoietic stem cell transplantations should be performed as usual. Low-grade lymphomas should only be treated when strictly indicated, maintenance can be postponed. Other myeloid neoplasia and their therapies cause imunosupression; dose adjustment is recommended but no brisk stopping. Sickle cell anemia patients are highly succeptible to severe COVID-19 course. Thrombocytopenia and procoagulant state are associated with severe courses of COVID-19, requiring an individualized therapy. No data indicate a risk of SARS-CoV-2 transmission through blood product transfusion.

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