• Luiz Rogério de Carvalho Oliveira, Anderson José, Elaine Cristina Polleti Dias, Cíntia Ruggero, Camila Viteli Molinari, and Paulo Antonio Chiavone.
• Santa Casa de São Paulo.
• Rev Bras Ter Intensiva. 2006 Jun 1; 18 (2): 131-6.

Background And ObjectivesThe weaning of mechanical ventilation is the process of transition from mechanical ventilation to spontaneous. The actual practice weaning reveals that the empirism is insufficient and inadequate. On the other side, the standardization of the weaning provides best conductions in the process. The objective of this study was to evaluate the effects of the application of a weaning protocol in an intensive care unit.MethodsMethodIt was included in this study all the patients in program of liberation from the mechanical ventilation, in which the evolution of the weaning was followed by the utilization of a pre-establish protocol and publicated by the service.ResultsIt was studied 127 patients. In 91% (115) of the patients we had success in the weaning and unsuccess in 9% (12). The non-invasive ventilation after the extubation was utilized in 19% (24) of them. None obit was observed. Comparing the group of the patients that had success with the failed group, there were no statistically significant variations observed in sex (p = 0.96), APACHE II (19.5 versus 18.6 p = 0.75), risk of obit (29% versus 22% p = 0.54), MIP (38 versus 32 cmH2O p = 0.17), duration of mechanical ventilation (6 versus 7 days p = 0.70), PaO2/FiO2 relation (324 versus 312 p = 0.83), weaning modality (PSV or T Tube p = 0.29). There were statistically significant variations observed in rapid shallow respiratory index (59 versus 77 p = 0.02) and duration of the weaning (1 versus 30 hours p < 0.001).ConclusionsThe weaning of the ventilation realized following the standardization brought improvement in its conduction, maintaining the high success index with low mortality.

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