• Paula Hernández, Lucia Polanco, Ignacio Santiago, Marina Fayos, and Carmen Valero.
• Departamento de Medicina Interna, Hospital Universitario Marqués de Valdecilla, IDIVAL, Universidad de Cantabria, Santander, España.
• Med Clin (Barc). 2021 Feb 12; 156 (3): 135-138.

IntroductionThe use of direct oral anticoagulants (DOACs) has modified anticoagulant therapy guidelines.ObjectivesTo determine changes and trends in the anticoagulant therapy of inpatients at an Internal medicine department.Material And Methods1584 inpatients of the internal medicine department (Hospital Marqués de Valdecilla. Santander) were studied in 2008 and 2018. The use of anticoagulant treatment, type of treatment, atrial fibrillation, comorbidity index, thrombotic and haemorrhagic complications were collected from the discharge reports.ResultsThe prevalence of anticoagulants increased by 5.7% (13.1% to 18.8%; P=0.002). The mean age increased by 7 years (76.2±11.1 yrs. vs. 83.6±8.9 yrs; P<0.001). The percentage of anticoagulated patients older than 75 yrs doubled. In 2018, 52% of anticoagulated took a DOAC. The prevalence of atrial fibrillation increased by 4% (30% vs. 34%; p=0.04) and by 24% that of anticoagulated atrial fibrillation by 24% (32.3% vs. 56%; P<0.001). The mean age is 6 years older (78.4±8.2 vs. 84.2±8.0; P<0.001).ConclusionsThe percentage of anticoagulated patients in internal medicine has increased, especially in those with atrial fibrillation.Copyright © 2020 Elsevier España, S.L.U. All rights reserved.

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