• Antiviral therapy · Jan 2009

    Review

    Antiviral treatment for chronic hepatitis C in illicit drug users: a systematic review.

    • Barbara Zanini and Alberto Lanzini.
    • Gastroenterology Unit, University and Spedali Civili of Brescia, Brescia, Italy.
    • Antivir. Ther. (Lond.). 2009 Jan 1; 14 (4): 467-79.

    AbstractAccording to recent World Health Organization data, approximately 170-200 million people worldwide are infected with hepatitis C virus (HCV). At present, illicit drug users (IDUs) constitute the largest group of individuals infected with HCV in industrial countries. Between 50% and 90% of IDUs are estimated to be positive for anti-HCV antibodies and most of the new infections occur in IDUs. The aim of our review is to focus on tertiary prevention of HCV infection among IDUs. We review strategies to prevent HCV infection and disease progression, attitude to antiviral treatment, access to specific HCV therapy and data of efficacy and safety of antiviral treatment among IDUs.

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