• Rev Assoc Med Bras (1992) · Oct 2020

    Review

    Association between vitamin D and cardioprotection in adult patients.

    • Gabriel Cavalcante Ferraz, Raul Ribeiro de Andrade, Fernando Minervo Pimentel Reis, Olavo Barbosa de Oliveira Neto, Clisivaldo Oliveira de Omena, Mario Jorge Jucá, Célio Fernando de Sousa-Rodrigues, and Fabiano Timbó Barbosa.
    • Acadêmico de Medicina do Centro Universitário CESMAC, Maceió, AL, Brasil.
    • Rev Assoc Med Bras (1992). 2020 Oct 1; 66 (10): 1444-1448.

    ObjectiveTo conduct a review of articles which have evaluated the relationship between vitamin D and cardioprotection in adult.MethodsA literature search was performed in the Pubmed and Scielo databases. The results were extracted from primary and secondary sources and will be presented in the form of a bibliographic review.ResultsTwenty-three articles were identified from the electronic search that reported on physiological mechanisms relating the vitamin D axis and the cardiovascular system through receptors. Of the ten studies that evaluated the therapeutic effect of vitamin D in cardiovascular diseases, none reported significant results.ConclusionThe articles assessed in this review did not demonstrate a cardioprotective effect of vitamin D, despite the epidemiological correlation of vitamin D deficiency with a higher prevalence of cardiovascular diseases.

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