• Zhi-Lei Wang, Juan Zhang, Dong-Qing Du, Feng-Jun Ma, Xiao Yan, Chen Chen, and Yu-Xia Ma.
• Department of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Shandong, Jinan.
• Medicine (Baltimore). 2020 Nov 13; 99 (46): e23198e23198.

BackgroundCOVID-9 has become a global pandemic with severe health issues around the world. However, there is still no effective drug to treat the disease, and many studies have shown that moxibustion plays a positive role in adjuvant treatment of COVID-19. Therefore, this meta-analysis is designed to evaluate the efficacy of moxibustion for COVID-19.MethodsThe relevant randomized controlled trials will be systematically retrieved from the electronic database, including PubMed, Embase, Cochrane Clinical Trials Database, Web of Science, and China National Knowledge Infrastructure, without restrictions on publication status and language. Two reviewers will independently review all included studies and assess the risk of bias. Two reviewers will independently extract data from the included studies based on a pre-designed standardized form. Any disagreements will be resolved by consensus. The meta-analysis will be performed with RevMan (V5.3.5) software.ResultThe results of this study will be published in a peer-reviewed journal.ConclusionThis ongoing meta-analysis will provide up-to-date evidence of the efficacy of moxibustion for patients with COVID-19.RegistrationThe meta-analysis has been prospectively registered in PROSPERO (CRD42020211910).

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