• Sevcan Tuğ Bozdoğan, Selim Büyükkurt, Sinem Özer, and Atıl Bişgin.
• Department of Medical Genetics, Faculty of Medicine, Çukurova University, Adana, Turkey
• Turk J Med Sci. 2021 Apr 30; 51 (2): 657-660.

Background/AimThe aim of this study was to summarize the experiences of a single medical center for genetic diagnosis and treatment of prenatal patients.Materials And MethodsThis study includes a retrospective data analysis of 2843 prenatally investigated cases using invasive methods during a 6-year period (2013–2019) at a single tertiary care center.ResultsChromosomal abnormalities were detected in 80 out of 1221 amniotic fluid samples;,178 out of 1608 chorionic villus samples, and 1 out of 14 cordocentesis samples. The most common chromosomal abnormality was trisomy 21. At least one mutation was detected in 63 of the 152 molecular tests performed on fetuses.ConclusionClinical procedures such as ultrasounds and genetic tests are able to provide a better clinical follow-up for pregnant women about the possible congenital anomalies or any genetic condition, with proper genetic counseling and testing methodology.This work is licensed under a Creative Commons Attribution 4.0 International License.

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