• J. Investig. Med. · Dec 2020

    Review

    Advances in the management of atrial fibrillation with a special focus on non-pharmacological approaches to prevent thromboembolism: a review of current recommendations.

    • Malini Riddle, Richard McCallum, Chandra Prakash Ojha, Timir Kumar Paul, Vineet Gupta, David Alan Baran, Bharat Ved Prakash, Amogh Misra, Adriana Camila Mares, Moeen Abedin, Archana Kedar, Venkatachalam Mulukutla, Ahmed Ibrahim, and Harsha Nagarajarao.
    • Paul L Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas, USA.
    • J. Investig. Med. 2020 Dec 1; 68 (8): 1317-1333.

    AbstractAtrial fibrillation (AFIB) is the most common heart rhythm abnormality and is associated with significant morbidity and mortality. While the treatment of AFIB involves strategies of rate with or without rhythm control, it is also essential to strategize appropriate therapies to prevent thromboembolic complications arising from AFIB. Previously, anticoagulation was the main treatment option which exposed patients to higher than usual risk of bleeding. However, with the advent of new technology, novel therapeutic options aimed at surgical or percutaneous exclusion or occlusion of the left atrial appendage in preventing thromboembolic complications from AFIB have evolved. This review evaluates recent advances and therapeutic options in treating AFIB with a special focus on both surgical and percutaneous interventions which can reduce and/or eliminate thromboembolic complications of AFIB.© American Federation for Medical Research 2020. No commercial re-use. See rights and permissions. Published by BMJ.

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