• Clin Med (Lond) · Nov 2020

    Rheumatoid arthritis and bone health.

    • Shanze Ashai and Nicholas C Harvey.
    • MRC Lifecourse Epidemiology Unit, Southampton, UK.
    • Clin Med (Lond). 2020 Nov 1; 20 (6): 565567565-567.

    AbstractRheumatoid arthritis (RA) is an inflammatory arthropathy affecting 1% of the population, with a female predominance. Systemic inflammation is a key component of RA disease; corticosteroids are often required to rapidly control disease activity. Both inflammation and corticosteroids, however, have an adverse effect on bone mineral density, potentially resulting in osteoporosis and an increased risk of fractures. In this article, we describe the link between RA and impaired bone health, together with appropriate strategies to maintain bone density and reduce fracture risk. Key approaches include achieving adequate control of inflammation, minimising corticosteroid use, monitoring bone mineral density and intervening with antiosteoporosis medications when indicated.© Royal College of Physicians 2020. All rights reserved.

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