[The early use of sepsis scores to predict respiratory failure

Revista clínica española · May 2022

Case Reports

[The early use of sepsis scores to predict respiratory failure and mortality in non-ICU patients with COVID-19].

This observational retrospective study aimed to investigate the usefulness of Sequential Organ Failure Assessment (SOFA), Quick SOFA (qSOFA), National Early Warning Score (NEWS), and quick NEWS in predicting respiratory failure and death among patients with COVID-19 hospitalized outside of intensive care units (ICU). We included 237 adults hospitalized with COVID-19 who were followed-up on for one month or until death. Respiratory failure was defined as a PaO2/FiO2 ratio ≤ 200 mmHg or the need for mechanical ventilation. ⋯ Regarding mortality, SOFA was more accurate than the other scores. In conclusion, sepsis scores are useful for predicting respiratory failure and mortality in COVID-19 patients. A NEWS score ≥ 4 was found to be the best cutoff point for predicting respiratory failure.

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- A Lalueza, J Lora-Tamayo, C de la Calle, J Sayas-Catalán, E Arrieta, G Maestro, M Mancheño-Losa, Á Marchán-López, R Díaz-Simón, R García-García, M Catalán, A García-Reyne, B de Miguel-Campo, C Lumbreras, and Grupo COVID 12.
- Servicio de Medicina Interna, Hospital Universitario 12 de Octubre, Madrid, España.
- Rev Clin Esp. 2022 May 1; 222 (5): 293-298.
AbstractThis observational retrospective study aimed to investigate the usefulness of Sequential Organ Failure Assessment (SOFA), Quick SOFA (qSOFA), National Early Warning Score (NEWS), and quick NEWS in predicting respiratory failure and death among patients with COVID-19 hospitalized outside of intensive care units (ICU). We included 237 adults hospitalized with COVID-19 who were followed-up on for one month or until death. Respiratory failure was defined as a PaO2/FiO2 ratio ≤ 200 mmHg or the need for mechanical ventilation. Respiratory failure occurred in 77 patients (32.5%), 29 patients (12%) were admitted to the ICU, and 49 patients (20.7%) died. Discrimination of respiratory failure was slightly higher in NEWS, followed by SOFA. Regarding mortality, SOFA was more accurate than the other scores. In conclusion, sepsis scores are useful for predicting respiratory failure and mortality in COVID-19 patients. A NEWS score ≥ 4 was found to be the best cutoff point for predicting respiratory failure.© 2020 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.

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[The early use of sepsis scores to predict respiratory failure and mortality in non-ICU patients with COVID-19].

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