• Am. J. Med. Sci. · Jan 2021

    Review Case Reports

    An Unusual Presentation of Aggressive Primary Invasive Adenocarcinoma of Lung.

    • Divya Thimmareddygari, Amr Ramahi, Kok Hoe Chan, Rutwik Patel, Sharath Bellary, Hari Sharma, and Richard Miller.
    • Department of Medical Education, Saint Michael's Medical Centre, New York Medical College, New Jersey, USA. Electronic address: divyamounisha.t@gmail.com.
    • Am. J. Med. Sci. 2021 Jan 1; 361 (1): 118-125.

    AbstractBilateral diffuse infiltrates on chest imaging can present a diagnostic challenge due to a broader differential diagnosis which includes pulmonary and non-pulmonary causes. Malignancy is generally not considered under differential diagnosis at the time of initial presentation. Here we present a case of primary adenocarcinoma of lung manifesting as diffuse bilateral infiltrates on imaging. Our case is unique in regards to its acute presentation, rapid progression to respiratory failure, ultimately leading to the demise of the patient. This indicates the aggressive nature of this malignancy and its variable presentation, like male gender and young age, thus emphasizing the importance of entertaining malignancy in such presentations, especially if there is no response to conventional antibiotic therapy.Copyright © 2020 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

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