• J Fleet, C Sok, E R Randall, and A M Cyna.
• University of South Australia, Clinical Health Sciences, Adelaide, South Australia, Australia. Electronic address: Julie.fleet@unisa.edu.au.
• Int J Obstet Anesth. 2021 Feb 1; 45: 138-141.

BackgroundIn 2017, a South Australia Perinatal Practice Guideline was introduced state-wide for the use of subcutaneous fentanyl for labour analgesia as a replacement for intramuscular pethidine. We retrospectively reviewed the implementation of this practice change in our institution.MethodsA retrospective review of maternal and neonatal case notes for the first 100 women administered subcutaneous fentanyl in labour at a single tertiary referral centre for maternity care, between February and June 2017.ResultsOf the 102 women administered subcutaneous fentanyl, the majority (55%) were primipara, with an average maternal age of 29 years and body mass index of 27 kg/m2. The median total fentanyl dose administered was 200 µg and the average time from last dose to birth was 3 h. The majority of women (70%) did not require additional rescue labour analgesia and 80% had a spontaneous vaginal birth. All neonates had a 5-min Apgar score >7. The median Apgar score at 1 and 5 min was 9. No neonate had an arterial cord blood pH <7.1. The mean arterial and venous cord blood pH was 7.3. The average time for neonates to establish breathing was 1 min and the median postnatal length of stay was two days.ConclusionsSubcutaneous fentanyl for labour analgesia appears effective and has a low incidence of adverse events.Copyright © 2020 Elsevier Ltd. All rights reserved.

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