• Atencion primaria · Dec 2007

    Randomized Controlled Trial Multicenter Study

    [Therapy compliance in cases of hyperlipaemia, as measured through electronic monitors. Is a reminder calendar to avoid forgetfulness effective?].

    • Emilio Márquez Contreras, José Joaquín Casado Martínez, Juan Motero Carrasco, José Luis Martín de Pablos, Rosa Chaves González, Carmen Losada Ruiz, and Pastoriza VilasJosé CarlosJC.
    • Medicina Familiar y Comunitaria, Centro de Salud la Orden, Distrito Huelva-Costa, Huelva, España. emarquezc@papps.org
    • Aten Primaria. 2007 Dec 1; 39 (12): 661668661-8.

    ObjectiveTo analyse the efficacy of the intervention with a calendar reminder of the medication taking in the treatment of the hyperlipidemias.DesignControlled, randomised clinical trial.SettingTwelve clinics at 5 primary care centres, Spain.ParticipantsTwo hundred and twenty people diagnosed with hypercholesterolaemia according to Spanish Consensus criteria were chosen.InterventionTwo groups were formed. The control group (CG) of 110 patients, who received the doctor's normal treatment; and the Intervention group (IG) of 110 patients, who received in addition a calendar remider of medication taking.Main MeasurementsMeausured of compliance was performed by moniotrs electronic (MEMS) and cholesterol, triglycerides, HDL-C, and LDL-C determined at the start, and at the third and sixth months. Percentages of patients complying (80%-110%), the mean compliance percentage and the degree of control were compared. The reduction of absolute and relative risk (RAR and RRR) and the mean number of people that required an intervention in order to avoid non-compliance (NI) were calculated.ResultsOne hundred and eighty eight people (85.45%) completed the survey, 96 in the IG and 92 in the CG; 26.55% were non compliers with the therapy (CI, +/-6.3%) (IG, 10.5%, CI, +/-4.6%; CG, 42.6%, CI, +/-10.1% [P<.0001]). Mean compliance ran at 88,1% (IC, +/-4.6%) overall, at 92% (CI, +/-5.4%) in the IG and at 84% (CI, +/-7.4%) in the IG (P<.05). The RAR was 32.1%, the RRR 75.35%, and the NI was 3.1 patients. The patients with cholesterol controlled ran at 66.7% (CI, +/-9.4%) in the IG and 41.2% in the CG (P<.001).ConclusionsThe calendar reminder intervention is an efficacious way of improving the percentage of patients complying with lipaemia treatment.

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