• J. Matern. Fetal. Neonatal. Med. · Jan 2007

    Should we continue screening rhesus D positive women for the development of atypical antibodies in late pregnancy?

    • A A Adeniji, I Fuller, T Dale, and S W Lindow.
    • Hull and East Yorkshire Hospitals, Hull Royal Infirmary, Hull, UK. aderonkeadeniji@hotmail.com
    • J. Matern. Fetal. Neonatal. Med. 2007 Jan 1; 20 (1): 59-61.

    ObjectiveThe purpose of this study was to calculate the incidence of the new development of atypical antibodies (other than anti-rhesus D) in women attending for antenatal care, and to assess the clinical impact and cost-effectiveness of a second test to detect these antibodies.MethodA three-year retrospective analysis was undertaken to calculate the number of rhesus positive women who developed new antibodies in the last trimester of pregnancy.ResultsOf 13,143 rhesus positive women, 20 (0.15%) developed new antibodies; fetal outcome was not compromised in any of these cases.ConclusionRepeat testing in late pregnancy would appear an unnecessary expense in our population.

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