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JBI Database System Rev Implement Rep · Jun 2017
Effects of dexamethasone on sugammadex reversal times of rocuronium: a systematic review protocol.
- Cassie R Held and Mackenzie D Sullivan.
- The Center for Translational Research: a Joanna Briggs Institute Center of Excellence, Fort Worth, Texas, USA.
- JBI Database System Rev Implement Rep. 2017 Jun 1; 15 (6): 1543-1551.
Review Question/ObjectiveThe objective of the review is to identify the effect of dexamethasone on reversal times of rocuronium when utilizing sugammadex as the reversal agent. The incidence of the prolonged time to extubation in patients who have received concurrent dexamethasone and sugammadex therapies as opposed to those who have not received dexamethasone will also be examined.The proposed PICO question is as follows: In patients undergoing reversal of aminosteroidal neuromuscular blockade with rocuronium, does dexamethasone administration affect sugammadex reversal times, as compared to patients who have not received dexamethasone?
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