• P Amami, I Dekker, S Piacentini, F Ferré, L M Romito, A Franzini, E M J Foncke, and A Albanese.
• Neurologia I, Fondazione Istituto Neurologico Carlo Besta, Milano, Italy.
• J. Neurol. Neurosurg. Psychiatr.. 2015 May 1;86(5):562-4.

ObjectiveTo document the occurrence of impulse control behaviours (ICBs) in patients with Parkinson's disease after 3 years of continuous deep brain stimulation (DBS) of the subthalamic nucleus (STN).MethodsDetailed neurological and ICB assessments were performed before STN DBS and up to 3 years after implant.Results13 out of 56 patients (23.2%) had ICBs at baseline; they took higher doses of dopamine agonists (DAA). Three years after implant 11 had fully remitted with a 60.8% reduction of DAA medication; the remaining two, who had a similar medication reduction, had only compulsive eating, having recovered from hypersexuality. Six of the 43 patients without ICBs at baseline (14%) developed transient de novo ICBs after implant; none of them had ICBs at the 3-year observation.ConclusionsICBs were abolished in patients 3 years after STN DBS and DAA dosages were lowered. New ICBs may occur after implant and are transient in most cases. Compulsive eating may be specifically related to STN stimulation.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

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