• Eur J Case Rep Intern Med · Jan 2020

    False-Negative Nasopharyngeal Swab RT-PCR Assays in Typical COVID-19: Role of Ultra-low-dose Chest CT and Bronchoscopy in Diagnosis.

    • Marco Marando, Adriana Tamburello, and Pietro Gianella.
    • General Internal Medicine, Ente Ospedaliero Cantonale, Lugano, Switzerland.
    • Eur J Case Rep Intern Med. 2020 Jan 1; 7 (7): 001680.

    AbstractOn 11 March 2020, the WHO declared COVID-19 a pandemic and global health emergency. We describe the clinical features and role of ultra-low-dose chest computed tomography (CT) and bronchoscopy in the diagnosis of coronavirus disease (COVID-19). In our patient, who was highly suggestive clinically and radiologically for COVID-19, we had two false-negative results for nasopharyngeal and oral swab reverse-transcriptase polymerase chain reaction (RT-PCR) assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Eventually, we confirmed the diagnosis using bronchoscopy and bronchoalveolar lavage (BAL).© EFIM 2020.

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