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- Alain R Thierry and Benoit Roch.
- Research Institute of Cancerology of Montpellier, INSERM U1194, IRCM, ICM, Université de Montpellier, Montpellier, F-34298, France.
- Clin. Sci. 2020 Jun 26; 134 (12): 1295-1300.
AbstractWe demonstrate that the general clinical conditions, risk factors and numerous pathological and biological features of COVID-19 are analogous with various disorders caused by the uncontrolled formation of neutrophil extracellular traps and their by-products. Given the rapid evolution of this disease's symptoms and its lethality, we hypothesize that SARS-CoV2 evades innate immune response causing COVID-19 progresses under just such an amplifier loop, leading to a massive, uncontrolled inflammation process. This work allows us to propose new strategies for treating the pandemic.© 2020 The Author(s).
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