• Med. Clin. North Am. · Jan 2021

    Review

    Update on Indigestion.

    • Alia Chisty.
    • Division of General Internal Medicine, Penn State College of Medicine, Penn State Health Milton S. Hershey Medical Center, 500 University Drive, PO Box 850, Hershey, PA 17033, USA. Electronic address: achisty@pennstatehealth.psu.edu.
    • Med. Clin. North Am. 2021 Jan 1; 105 (1): 19-30.

    AbstractDyspepsia affects a large percentage of the general population and can lead to lost work productivity and reduced quality of life. Patients with dyspepsia younger than 60 should not routinely undergo endoscopy but instead should pursue Helicobacter pylori test-and-treat approach. For patients 60 and older, endoscopy should be performed. Patients without any identifiable cause for their symptoms are diagnosed with functional dyspepsia. Guideline-based treatment includes H pylori eradication and proton pump inhibitor use. If acid suppression is not adequate, treatment with a tricyclic antidepressant followed by a prokinetic agent and psychological therapy are considered. Complementary therapies are not recommended due to limited evidence.Copyright © 2020 Elsevier Inc. All rights reserved.

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