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Am J Obstet Gynecol MFM · Aug 2020
Case ReportsFalse-negative testing for severe acute respiratory syndrome coronavirus 2: consideration in obstetrical care.
- Jeannie C Kelly, Michael Dombrowksi, Micaela O'Neil-Callahan, Annessa S Kernberg, Antonina I Frolova, and Molly J Stout.
- Division of Maternal-Fetal Medicine, Washington University in St Louis, St Louis, MO.
- Am J Obstet Gynecol MFM. 2020 Aug 1; 2 (3): 100130.
AbstractBecause the obstetrical population seems to have a high proportion of asymptomatic patients who are carriers of severe acute respiratory syndrome coronavirus 2, universal testing has been proposed as a strategy to risk-stratify all obstetrical admissions and guide infection prevention protocols. Here, we describe a case of a critically ill obstetrical patient with all the clinical symptoms of coronavirus disease 2019 and 3 false-negative results of nasopharyngeal swabs for molecular testing. We review and discuss the uncertain clinical characteristics of current severe acute respiratory syndrome coronavirus 2 molecular testing and the implications of false-negative results in the obstetrical population.© 2020 Elsevier Inc. All rights reserved.
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