• Ji-Chan Shi, Zhi-Jie Yu, Gui-Qing He, Wei Chen, Xin-Chun Ye, Zheng-Xing Wu, Xiao-Qu Zhu, Jiao-Zhi Pan, and Xian-Gao Jiang.
• Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, Zhejiang, China.
• J Natl Med Assoc. 2021 Apr 1; 113 (2): 212217212-217.

ObjectiveTo investigate and evaluate the clinical features of patients infected with the 2019 novel coronavirus (COVID-19) outside of Wuhan.Methods105 patients admitted to our hospital with clinical- and laboratory-confirmed COVID-19 infection were studied. Data were collected from January 17, 2020 to March 5, 2020.Results105 patients (57 male and 48 female) were confirmed to have COVID-19 infection. Among the 105 patients, 55 (52%) had made short trips to Wuhan during the two weeks before the onset of illness, and these were the first-generation confirmed cases. An exact date of close contact with someone in Wenzhou with confirmed or suspected COVID-19 infection from Wuhan (the second-generation confirmed cases) could be provided by 38 (36%) patients. Of the remaining patients, six (6%; the third-generation confirmed cases) were familial clusters of the second-generation confirmed cases, three (3%) had no definite epidemiological features, and 16 (15%) were from the same location as for the case report.ConclusionDue to the infectiousness of COVID-19, patients with infections should be diagnosed and treated as early as possible after developing fever symptoms or showing other clinical characteristics or imaging features. With respect to high-risk cases, we must focus on any complications that arise and take effective measures to treat them immediately. This will significantly improve the prognosis of patients with severe infections.Copyright © 2020 National Medical Association. Published by Elsevier Inc. All rights reserved.

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