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Yonsei medical journal · Dec 2020
Case ReportsA Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen.
- Haein Bak, Hayeon Kim, Sieun Lee, Yoonseok Lee, Soo Min Bang, and Young Sun Lee.
- Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
- Yonsei Med. J. 2020 Dec 1; 61 (12): 1060-1063.
AbstractVanishing bile duct syndrome (VBDS) is a rare disease characterized by ductopenia and cholestasis, and is linked to immunological damage to the bile duct system. VBDS can be triggered by infection, ischemia, autoimmune diseases, adverse drug reactions, and humoral factors associated with malignancy. A few cases of VBDS associated with nonsteroidal anti-inflammatory drug-related drug-induced liver injury (DILI) have been reported. Here, we report a case of a 29-year-old patient who developed DILI that progressed to VBDS after the administration of pelubiprofen.© Copyright: Yonsei University College of Medicine 2020.
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