• Anasthesiol Intensivmed Notfallmed Schmerzther · Aug 2004

    Review

    [Xenon - noble gas with organprotective properties].

    • B Preckel, N Weber, and W Schlack.
    • Klinik für Anästhesiologie, Universitätsklinikum Düsseldorf. preckel@med.uni-duesseldorf.de
    • Anasthesiol Intensivmed Notfallmed Schmerzther. 2004 Aug 1; 39 (8): 456-62.

    AbstractBesides it's anaesthetic properties, xenon may induce biological effects that may protect various organs from ischaemia-reperfusion injury. Xenon is an antagonist of the NMDA-receptor and reduces the neuronal injury mediated via these receptors. In contrast to other NMDA-receptor antagonists, xenon has no neurotoxic side effects. Xenon also protects the heart in ischaemia-reperfusion situations. Xenon reduces the post-ischaemic reperfusion injury and offers cardioprotection by inducing pharmacological preconditioning. These organ protective properties of xenon might be useful in special clinical situations.

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