• Medicine · Dec 2020

    The efficacy and safety of Yuxingcao eye drops in the treatment of COVID-19 conjunctivitis: A protocol for a systematic review.

    • Jiajun Wu, Liqu Pu, Hui Zhou, Wenjia Qu, Dandan Zhao, Chunmeng Liu, Xuewen Dong, and Fuwen Zhang.
    • School of Eye.
    • Medicine (Baltimore). 2020 Dec 4; 99 (49): e23093e23093.

    BackgroundCoronavirus disease 2019 (COVID-19) is a global pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). There is no specific cure for this disease, and the clinical management mainly depends on supportive treatment. This disease may affect SARS-CoV-2 conjunctivitis. Yuxingcao eye drops is used in treating COVID-19 conjunctivitis in China.MethodsA comprehensive literature search will be conducted. Two methodological trained researchers will read the title, abstract, and full texts and independently select the qualified literature according to inclusion and exclusion criteria. After assessment of the risk of bias and data extraction, we will conduct meta-analyses for outcomes related to COVID-19 conjunctivitis. The heterogeneity of data will be investigated by Cochrane X and I tests. Then publication bias assessment will be conducted by funnel plot analysis and Egger test.ResultsThe results of our research will be published in a peer-reviewed journal.ConclusionOur study aims to systematically present the clinical evidence of Yuxingcao eye drops in treating COVID-19 conjunctivitis, which will be of significant meaning for further research and clinical practice.Prospero Registration NumberPROSPERO CRD42020209059.

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